Construction of a Pseudoreceptor That Mediates Transduction by Adenoviruses Expressing a Ligand in Fiber or Penton Base

Modification of adenovirus to achieve tissue specific targeting for the delivery of therapeutic genes requires both the ablation of its native tropism and the introduction of specific, novel interactions. Inactivation of the native receptor interactions, however, would cripple the virus for growth i...

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Bibliografische Detailangaben

Veröffentlicht in:	J Virol
Hauptverfasser:	Einfeld, David A., Brough, Douglas E., Roelvink, Peter W., Kovesdi, Imre, Wickham, Thomas J.
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Microbiology (ASM) 1999
Schlagworte:	Gene Therapy
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC112945/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10516019/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.73.11.9130-9136.1999
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