A vital role of tubulin-tyrosine-ligase for neuronal organization

Tubulin is subject to a special cycle of detyrosination/tyrosination in which the C-terminal tyrosine of α-tubulin is cyclically removed by a carboxypeptidase and readded by a tubulin-tyrosine-ligase (TTL). This tyrosination cycle is conserved in evolution, yet its physiological importance is unknow...

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Bibliographic Details
Main Authors: Erck, Christian, Peris, Leticia, Andrieux, Annie, Meissirel, Claire, Gruber, Achim D., Vernet, Muriel, Schweitzer, Annie, Saoudi, Yasmina, Pointu, Hervé, Bosc, Christophe, Salin, Paul A., Job, Didier, Wehland, Juergen
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2005
Subjects:
Biological Sciences
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1129054/
https://ncbi.nlm.nih.gov/pubmed/15899979
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0409626102
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