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Expression of Hepatitis C Virus Proteins Inhibits Signal Transduction through the Jak-STAT Pathway

Hepatitis C virus (HCV) infection is a leading cause of liver disease worldwide. Alpha interferon (IFN-α) therapy of chronic hepatitis C leads to a sustained response in 10 to 20% of patients only. The mechanisms of viral persistence and the pathogenesis of hepatitis C are poorly understood. We esta...

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Detalhes bibliográficos
Main Authors: Heim, Markus H., Moradpour, Darius, Blum, Hubert E.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 1999
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC112866/
https://ncbi.nlm.nih.gov/pubmed/10482599
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