Viral Load and a Locus on Chromosome 11 Affect the Late Clinical Disease Caused by Theiler’s Virus

Theiler’s virus causes a persistent infection and a demyelinating disease of mice which is a model for multiple sclerosis. Susceptibility to viral persistence maps to several loci, including the interferon gamma locus. Inactivating the gene coding for the interferon gamma receptor makes 129/Sv mice...

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Bibliografische Detailangaben

Veröffentlicht in:	J Virol
Hauptverfasser:	Aubagnac, Stéphanie, Brahic, Michel, Bureau, Jean-François
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Microbiology (ASM) 1999
Schlagworte:	Pathogenesis and Immunity
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC112810/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10482543/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.73.10.7965-7971.1999
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