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Viral Load and a Locus on Chromosome 11 Affect the Late Clinical Disease Caused by Theiler’s Virus
Theiler’s virus causes a persistent infection and a demyelinating disease of mice which is a model for multiple sclerosis. Susceptibility to viral persistence maps to several loci, including the interferon gamma locus. Inactivating the gene coding for the interferon gamma receptor makes 129/Sv mice...
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Main Authors: | , , |
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Format: | Artigo |
Jezik: | Inglês |
Izdano: |
American Society for Microbiology
1999
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Teme: | |
Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC112810/ https://ncbi.nlm.nih.gov/pubmed/10482543 |
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