Systematic Excision of Vector Sequences from the BAC-Cloned Herpesvirus Genome during Virus Reconstitution

Recently the mouse cytomegalovirus (MCMV) genome was cloned as an infectious bacterial artificial chromosome (BAC) (M. Messerle, I. Crnković, W. Hammerschmidt, H. Ziegler, and U. H. Koszinowski, Proc. Natl. Acad. Sci. USA 94:14759–14763, 1997). The virus obtained from this construct is attenuated in...

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Détails bibliographiques
Auteurs principaux: Wagner, Markus, Jonjić, Stipan, Koszinowski, Ulrich H., Messerle, Martin
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 1999
Sujets:
Replication
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC112796/
https://ncbi.nlm.nih.gov/pubmed/10400809
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