Systematic Excision of Vector Sequences from the BAC-Cloned Herpesvirus Genome during Virus Reconstitution

Recently the mouse cytomegalovirus (MCMV) genome was cloned as an infectious bacterial artificial chromosome (BAC) (M. Messerle, I. Crnković, W. Hammerschmidt, H. Ziegler, and U. H. Koszinowski, Proc. Natl. Acad. Sci. USA 94:14759–14763, 1997). The virus obtained from this construct is attenuated in...

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Bibliografske podrobnosti
Main Authors: Wagner, Markus, Jonjić, Stipan, Koszinowski, Ulrich H., Messerle, Martin
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 1999
Teme:
Replication
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC112796/
https://ncbi.nlm.nih.gov/pubmed/10400809
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