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E4ORF3 Requirement for Achieving Long-Term Transgene Expression from the Cytomegalovirus Promoter in Adenovirus Vectors

Analysis of transgene expression under the control of the cytomegalovirus (CMV) promoter from adenovirus vectors in which the E4 region was modified indicated that E4ORF3 is required for long-term expression in the murine lung. CMV promoter truncation led to the persistence of expression in the abse...

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Published in:J Virol
Main Authors: Armentano, Donna, Smith, Michael P., Sookdeo, Cathleen C., Zabner, Joseph, Perricone, Michael A., St. George, Judith A., Wadsworth, Samuel C., Gregory, Richard J.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 1999
Subjects:
Gene Therapy
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC112791/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10400804/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.73.8.7031-7034.1999
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