Ovine Adenovirus Vectors Overcome Preexisting Humoral Immunity against Human Adenoviruses In Vivo

Recombinant human adenoviruses (hAd) have become widely used as tools to achieve efficient gene transfer. However, successful application of hAd-derived vectors in clinical trials is limited due to immunological and potential safety problems inherent in their human origin. In this study, we describe...

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Detalhes bibliográficos

Publicado no:	J Virol
Principais autores:	Hofmann, Christian, Löser, Peter, Cichon, Günter, Arnold, Wolfgang, Both, Gerald W., Strauss, Michael
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1999
Assuntos:	Gene Therapy
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC112778/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10400791/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.73.8.6930-6936.1999
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