Ovine Adenovirus Vectors Overcome Preexisting Humoral Immunity against Human Adenoviruses In Vivo

Recombinant human adenoviruses (hAd) have become widely used as tools to achieve efficient gene transfer. However, successful application of hAd-derived vectors in clinical trials is limited due to immunological and potential safety problems inherent in their human origin. In this study, we describe...

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Bibliografski detalji

Izdano u:	J Virol
Glavni autori:	Hofmann, Christian, Löser, Peter, Cichon, Günter, Arnold, Wolfgang, Both, Gerald W., Strauss, Michael
Format:	Artigo
Jezik:	Inglês
Izdano:	American Society for Microbiology (ASM) 1999
Teme:	Gene Therapy
Online pristup:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC112778/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10400791/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.73.8.6930-6936.1999
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