Variability of Human Systemic Humoral Immune Responses to Adenovirus Gene Transfer Vectors Administered to Different Organs

Administration of adenovirus (Ad) vectors to immunologically naive experimental animals almost invariably results in the induction of systemic anti-Ad neutralizing antibodies. To determine if the human systemic humoral host responses to Ad vectors follow a similar pattern, we evaluated the systemic...

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Autors principals: Harvey, Ben-Gary, Hackett, Neil R., El-Sawy, Tarek, Rosengart, Todd K., Hirschowitz, Edward A., Lieberman, Michael D., Lesser, Martin L., Crystal, Ronald G.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 1999
Matèries:
Gene Therapy
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC112758/
https://ncbi.nlm.nih.gov/pubmed/10400771
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