Variability of Human Systemic Humoral Immune Responses to Adenovirus Gene Transfer Vectors Administered to Different Organs

Administration of adenovirus (Ad) vectors to immunologically naive experimental animals almost invariably results in the induction of systemic anti-Ad neutralizing antibodies. To determine if the human systemic humoral host responses to Ad vectors follow a similar pattern, we evaluated the systemic...

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Main Authors: Harvey, Ben-Gary, Hackett, Neil R., El-Sawy, Tarek, Rosengart, Todd K., Hirschowitz, Edward A., Lieberman, Michael D., Lesser, Martin L., Crystal, Ronald G.
格式: Artigo
語言:Inglês
出版: American Society for Microbiology 1999
主題:
Gene Therapy
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC112758/
https://ncbi.nlm.nih.gov/pubmed/10400771
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