Antiapoptotic and Oncogenic Potentials of Hepatitis C Virus Are Linked to Interferon Resistance by Viral Repression of the PKR Protein Kinase

Hepatitis C virus (HCV) is prevalent worldwide and has become a major cause of liver dysfunction and hepatocellular carcinoma. The high prevalence of HCV reflects the persistent nature of infection and the large frequency of cases that resist the current interferon (IFN)-based anti-HCV therapeutic r...

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Vydáno v:	J Virol
Hlavní autoři:	Gale, Michael, Kwieciszewski, Bart, Dossett, Michelle, Nakao, Haruhisa, Katze, Michael G.
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	American Society for Microbiology (ASM) 1999
Témata:	Virus-Cell Interactions
On-line přístup:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC112733/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10400746/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.73.8.6506-6516.1999
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