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Antiapoptotic and Oncogenic Potentials of Hepatitis C Virus Are Linked to Interferon Resistance by Viral Repression of the PKR Protein Kinase

Hepatitis C virus (HCV) is prevalent worldwide and has become a major cause of liver dysfunction and hepatocellular carcinoma. The high prevalence of HCV reflects the persistent nature of infection and the large frequency of cases that resist the current interferon (IFN)-based anti-HCV therapeutic r...

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Bibliografiske detaljer
Udgivet i:J Virol
Principais autores: Gale, Michael, Kwieciszewski, Bart, Dossett, Michelle, Nakao, Haruhisa, Katze, Michael G.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 1999
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC112733/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10400746/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.73.8.6506-6516.1999
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