A Lysine-to-Arginine Change Found in Natural Alleles of the Human T-Cell Lymphotropic/Leukemia Virus Type 1 p12(I) Protein Greatly Influences Its Stability

The HTLV-1 singly spliced open reading frame I protein, p12(I), is highly unstable and appears to be necessary for persistent infection in rabbits. Here we demonstrate that p12(I) forms dimers through two putative leucine zipper domains and that its stability is augmented by specific proteasome inhi...

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Detalhes bibliográficos

Publicado no:	J Virol
Principais autores:	Trovato, Raffaella, Mulloy, James C., Johnson, Julie M., Takemoto, Shigeki, de Oliveira, Maria Pombo, Franchini, Genoveffa
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1999
Assuntos:	Transformation and Oncogenesis
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC112727/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10400740/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.73.8.6460-6467.1999
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