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Persistent Infection of Rhesus Macaques by the Rev-Independent Nef(−) Simian Immunodeficiency Virus SIVmac239: Replication Kinetics and Genomic Stability

We generated previously a Nef(−), replication-competent clone of SIVmac239 in which the Rev protein and the Rev-responsive element were replaced by the constitutive transport element (CTE) of simian retrovirus type 1 (A. S. von Gegerfelt and B. K. Felber, Virology 232:291–299, 1997). In the present...

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Main Authors: von Gegerfelt, Agneta S., Liska, Vladimir, Ray, Nancy B., McClure, Harold M., Ruprecht, Ruth M., Felber, Barbara K.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 1999
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC112685/
https://ncbi.nlm.nih.gov/pubmed/10364376
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