Transduction of Well-Differentiated Airway Epithelium by Recombinant Adeno-Associated Virus Is Limited by Vector Entry

The limitations of adeno-associated virus (AAV)-mediated vectors for lung-directed gene transfer were investigated by using differentiated human respiratory epithelium in air-liquid interface cultures. Transduction efficiency was high in undifferentiated cells and was enhanced in well-differentiated...

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Hlavní autoři: Bals, Robert, Xiao, Weidong, Sang, Nianli, Weiner, Daniel J., Meegalla, Rupalie L., Wilson, James M.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 1999
Témata:
Gene Therapy
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC112671/
https://ncbi.nlm.nih.gov/pubmed/10364362
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