Transduction of Well-Differentiated Airway Epithelium by Recombinant Adeno-Associated Virus Is Limited by Vector Entry

The limitations of adeno-associated virus (AAV)-mediated vectors for lung-directed gene transfer were investigated by using differentiated human respiratory epithelium in air-liquid interface cultures. Transduction efficiency was high in undifferentiated cells and was enhanced in well-differentiated...

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Detalhes bibliográficos

Publicado no:	J Virol
Principais autores:	Bals, Robert, Xiao, Weidong, Sang, Nianli, Weiner, Daniel J., Meegalla, Rupalie L., Wilson, James M.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1999
Assuntos:	Gene Therapy
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC112671/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10364362/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.73.7.6085-6088.1999
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