Generation of an Adenovirus Vector Lacking E1, E2a, E3, and All of E4 except Open Reading Frame 3
Toxicity and immunity associated with adenovirus backbone gene expression is an important hurdle to overcome for successful gene therapy. Recent efforts to improve adenovirus vectors for in vivo use have focused on the sequential deletion of essential early genes. Adenovirus vectors have been constr...
Збережено в:
| Опубліковано в:: | J Virol |
|---|---|
| Автори: | , , , , , , , |
| Формат: | Artigo |
| Мова: | Inglês |
| Опубліковано: |
American Society for Microbiology (ASM)
1999
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| Предмети: | |
| Онлайн доступ: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC112666/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10364357/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.73.7.6048-6055.1999 |
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