Induction of Adult T-Cell Leukemia-Like Lymphoproliferative Disease and Its Inhibition by Adoptive Immunotherapy in T-Cell-Deficient Nude Rats Inoculated with Syngeneic Human T-Cell Leukemia Virus Type 1-Immortalized Cells

Human T-cell leukemia virus type 1 (HTLV-1) has been shown to be the etiologic agent of adult T-cell leukemia (ATL), but the in vivo mechanism by which the virus causes the malignant transformation is largely unknown. In order to investigate the mechanisms of HTLV-1 leukemogenesis, we developed a ra...

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Détails bibliographiques
Auteurs principaux: Ohashi, Takashi, Hanabuchi, Shino, Kato, Hirotomo, Koya, Yoshihiro, Takemura, Fumiyo, Hirokawa, Katsuiku, Yoshiki, Takashi, Tanaka, Yuetsu, Fujii, Masahiro, Kannagi, Mari
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 1999
Sujets:
Pathogenesis and Immunity
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC112664/
https://ncbi.nlm.nih.gov/pubmed/10364355
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