Induction of Adult T-Cell Leukemia-Like Lymphoproliferative Disease and Its Inhibition by Adoptive Immunotherapy in T-Cell-Deficient Nude Rats Inoculated with Syngeneic Human T-Cell Leukemia Virus Type 1-Immortalized Cells

Human T-cell leukemia virus type 1 (HTLV-1) has been shown to be the etiologic agent of adult T-cell leukemia (ATL), but the in vivo mechanism by which the virus causes the malignant transformation is largely unknown. In order to investigate the mechanisms of HTLV-1 leukemogenesis, we developed a ra...

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Pubblicato in:	J Virol
Autori principali:	Ohashi, Takashi, Hanabuchi, Shino, Kato, Hirotomo, Koya, Yoshihiro, Takemura, Fumiyo, Hirokawa, Katsuiku, Yoshiki, Takashi, Tanaka, Yuetsu, Fujii, Masahiro, Kannagi, Mari
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 1999
Soggetti:	Pathogenesis and Immunity
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC112664/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10364355/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.73.7.6031-6040.1999
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