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Epstein-Barr Virus Nuclear Antigen 3C Interacts with Histone Deacetylase To Repress Transcription

EBNA3C can specifically repress the expression of reporter plasmids containing EBV Cp latency-associated promoter elements. Cp is normally the main promoter for EBNA mRNA initiation, so it appears that EBNA3C contributes to a negative autoregulatory control loop. By mutational analysis it was previo...

Ausführliche Beschreibung

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Bibliografische Detailangaben
Veröffentlicht in:J Virol
Hauptverfasser: Radkov, Stoyan A., Touitou, Robert, Brehm, Alex, Rowe, Martin, West, Michelle, Kouzarides, Tony, Allday, Martin J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology (ASM) 1999
Schlagworte:
Online-Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC112628/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10364319/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.73.7.5688-5697.1999
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