Epstein-Barr Virus Nuclear Antigen 3C Interacts with Histone Deacetylase To Repress Transcription

EBNA3C can specifically repress the expression of reporter plasmids containing EBV Cp latency-associated promoter elements. Cp is normally the main promoter for EBNA mRNA initiation, so it appears that EBNA3C contributes to a negative autoregulatory control loop. By mutational analysis it was previo...

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Main Authors: Radkov, Stoyan A., Touitou, Robert, Brehm, Alex, Rowe, Martin, West, Michelle, Kouzarides, Tony, Allday, Martin J.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 1999
Teme:
Virus-Cell Interactions
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC112628/
https://ncbi.nlm.nih.gov/pubmed/10364319
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