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The Anamnestic Neutralizing Antibody Response Is Critical for Protection of Mice from Challenge following Vaccination with a Plasmid Encoding the Japanese Encephalitis Virus Premembrane and Envelope Genes

For Japanese encephalitis (JE), we previously reported that recombinant vaccine-induced protection from disease does not prevent challenge virus replication in mice. Moreover, DNA vaccines for JE can provide protection from high challenge doses in the absence of detectable prechallenge neutralizing...

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Bibliografiske detaljer
Main Authors: Konishi, Eiji, Yamaoka, Masaoki, Khin-Sane-Win, Kurane, Ichiro, Takada, Kazuo, Mason, Peter W.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 1999
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC112610/
https://ncbi.nlm.nih.gov/pubmed/10364301
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