The Anamnestic Neutralizing Antibody Response Is Critical for Protection of Mice from Challenge following Vaccination with a Plasmid Encoding the Japanese Encephalitis Virus Premembrane and Envelope Genes

For Japanese encephalitis (JE), we previously reported that recombinant vaccine-induced protection from disease does not prevent challenge virus replication in mice. Moreover, DNA vaccines for JE can provide protection from high challenge doses in the absence of detectable prechallenge neutralizing...

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Main Authors: Konishi, Eiji, Yamaoka, Masaoki, Khin-Sane-Win, Kurane, Ichiro, Takada, Kazuo, Mason, Peter W.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 1999
Teme:
Vaccines and Antiviral Agents
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC112610/
https://ncbi.nlm.nih.gov/pubmed/10364301
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