Sequence Variations in Human Immunodeficiency Virus Type 1 Nef Are Associated with Different Stages of Disease

nef alleles derived from a large number of individuals infected with human immunodeficiency virus type 1 (HIV-1) were analyzed to investigate the frequency of disrupted nef genes and to elucidate whether specific amino acid substitutions in Nef are associated with different stages of disease. We con...

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Bibliographic Details
Main Authors: Kirchhoff, Frank, Easterbrook, Philippa J., Douglas, Nigel, Troop, Maxine, Greenough, Thomas C., Weber, Jonathan, Carl, Silke, Sullivan, John L., Daniels, Rod S.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 1999
Subjects:
Pathogenesis and Immunity
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC112607/
https://ncbi.nlm.nih.gov/pubmed/10364298
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