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Cell Cycle- and Vpr-Mediated Regulation of Human Immunodeficiency Virus Type 1 Expression in Primary and Transformed T-Cell Lines

Viral protein R (Vpr) of human immunodeficiency virus type 1 (HIV-1) transiently arrests cells in the G(2) phase of the cell cycle and is a weak transcriptional transactivator. We found that Vpr increased HIV-1 long terminal repeat (LTR) activity in all cells examined but, when expressed at high lev...

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Pubblicato in:J Virol
Autori principali: Gummuluru, Suryaram, Emerman, Michael
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology (ASM) 1999
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC112598/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10364289/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.73.7.5422-5430.1999
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