p53-Independent and -Dependent Requirements for E1B-55K in Adenovirus Type 5 Replication

The adenovirus type 5 mutant dl1520 was engineered previously to be completely defective for E1B-55K functions. Recently, this mutant (also known as ONYX-015) has been suggested to replicate preferentially in p53(−) and some p53(+) tumor cell lines but to be attenuated in primary cultured cells (C....

Täydet tiedot

Bibliografiset tiedot

Julkaisussa:	J Virol
Päätekijät:	Harada, Josephine N., Berk, Arnold J.
Aineistotyyppi:	Artigo
Kieli:	Inglês
Julkaistu:	American Society for Microbiology (ASM) 1999
Aiheet:	Virus-Cell Interactions
Linkit:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC112589/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10364280/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.73.7.5333-5344.1999
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