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Adenovirus-Mediated p21((WAF1/SDII/CIP1)) Gene Transfer Induces Apoptosis of Human Cervical Cancer Cell Lines

p21((WAF1/SDII/CIP1)) (p21) arrests cell growth by inhibiting cyclin-depend kinases. To explore the potential of using p21 for the gene therapy of cervical cancer, we infected human papillomavirus (HPV)-positive cervical cancer cells (HeLa, SiHa, and Z172) and HPV-negative cervical cancer cells (C33...

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Udgivet i:J Virol
Principais autores: Tsao, Yeou-Ping, Huang, Shyh-Jer, Chang, Junn-Liang, Hsieh, Jer-Tsong, Pong, Rey-Chen, Chen, Show-Li
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 1999
Fag:
Gene Therapy
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC112542/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10233960/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.73.6.4983-4990.1999
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