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Apelin, the Natural Ligand of the Orphan Seven-Transmembrane Receptor APJ, Inhibits Human Immunodeficiency Virus Type 1 Entry

In addition to the CCR5 and CXCR4 chemokine receptors, a subset of primary human immunodeficiency virus type 1 (HIV-1) isolates can also use the seven-transmembrane-domain receptor APJ as a coreceptor. A previously identified ligand of APJ, apelin, specifically inhibited the entry of primary T-tropi...

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Main Authors: Cayabyab, Mark, Hinuma, Shuji, Farzan, Michael, Choe, Hyeryun, Fukusumi, Shoji, Kitada, Chieko, Nishizawa, Naoki, Hosoya, Masaki, Nishimura, Osamu, Messele, Tsehaynesh, Pollakis, Georgios, Goudsmit, Jaap, Fujino, Masahiko, Sodroski, Joseph
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2000
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC112482/
https://ncbi.nlm.nih.gov/pubmed/11090199
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