Herpesvirus Saimiri vFLIP Provides an Antiapoptotic Function but Is Not Essential for Viral Replication, Transformation, or Pathogenicity

Apoptosis of infected cells is an important host defense mechanism, and many viruses have exploited antiapoptotic proteins that interfere with crucial cellular pathways. Viral FLICE inhibitory proteins (vFLIPs) are encoded by rhadinoviruses like herpesvirus saimiri, the related Kaposi's sarcoma...

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Detalhes bibliográficos
Main Authors: Glykofrydes, Diana, Niphuis, Henk, Kuhn, Eva M., Rosenwirth, Brigitte, Heeney, Jonathan L., Bruder, Joseph, Niedobitek, Gerald, Müller-Fleckenstein, Ingrid, Fleckenstein, Bernhard, Ensser, Armin
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2000
Assuntos:
Transformation and Oncogenesis
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC112475/
https://ncbi.nlm.nih.gov/pubmed/11090192
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