Herpesvirus Saimiri vFLIP Provides an Antiapoptotic Function but Is Not Essential for Viral Replication, Transformation, or Pathogenicity

Apoptosis of infected cells is an important host defense mechanism, and many viruses have exploited antiapoptotic proteins that interfere with crucial cellular pathways. Viral FLICE inhibitory proteins (vFLIPs) are encoded by rhadinoviruses like herpesvirus saimiri, the related Kaposi's sarcoma...

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Autores principales: Glykofrydes, Diana, Niphuis, Henk, Kuhn, Eva M., Rosenwirth, Brigitte, Heeney, Jonathan L., Bruder, Joseph, Niedobitek, Gerald, Müller-Fleckenstein, Ingrid, Fleckenstein, Bernhard, Ensser, Armin
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2000
Materias:
Transformation and Oncogenesis
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC112475/
https://ncbi.nlm.nih.gov/pubmed/11090192
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