Infection of Human Dendritic Cells by a Sindbis Virus Replicon Vector Is Determined by a Single Amino Acid Substitution in the E2 Glycoprotein

The ability to target antigen-presenting cells with vectors encoding desired antigens holds the promise of potent prophylactic and therapeutic vaccines for infectious diseases and cancer. Toward this goal, we derived variants of the prototype alphavirus, Sindbis virus (SIN), with differential abilit...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Autori principali: Gardner, Jason P., Frolov, Ilya, Perri, Silvia, Ji, Yaying, MacKichan, Mary Lee, zur Megede, Jan, Chen, Minchao, Belli, Barbara A., Driver, David A., Sherrill, Scott, Greer, Catherine E., Otten, Gillis R., Barnett, Susan W., Liu, Margaret A., Dubensky, Thomas W., Polo, John M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2000
Soggetti:
Vaccines and Antiviral Agents
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC112468/
https://ncbi.nlm.nih.gov/pubmed/11090185
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi