Infection of Human Dendritic Cells by a Sindbis Virus Replicon Vector Is Determined by a Single Amino Acid Substitution in the E2 Glycoprotein

The ability to target antigen-presenting cells with vectors encoding desired antigens holds the promise of potent prophylactic and therapeutic vaccines for infectious diseases and cancer. Toward this goal, we derived variants of the prototype alphavirus, Sindbis virus (SIN), with differential abilit...

Descripció completa

Guardat en:
Dades bibliogràfiques
Autors principals: Gardner, Jason P., Frolov, Ilya, Perri, Silvia, Ji, Yaying, MacKichan, Mary Lee, zur Megede, Jan, Chen, Minchao, Belli, Barbara A., Driver, David A., Sherrill, Scott, Greer, Catherine E., Otten, Gillis R., Barnett, Susan W., Liu, Margaret A., Dubensky, Thomas W., Polo, John M.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2000
Matèries:
Vaccines and Antiviral Agents
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC112468/
https://ncbi.nlm.nih.gov/pubmed/11090185
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars