Influenza A Virus NS1 Protein Prevents Activation of NF-κB and Induction of Alpha/Beta Interferon

The alpha/beta interferon (IFN-α/β) system represents one of the first lines of defense against virus infections. As a result, most viruses encode IFN antagonistic factors which enhance viral replication in their hosts. We have previously shown that a recombinant influenza A virus lacking the NS1 ge...

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Main Authors: Wang, Xiuyan, Li, Ming, Zheng, Hongyong, Muster, Thomas, Palese, Peter, Beg, Amer A., García-Sastre, Adolfo
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2000
Assuntos:
Virus-Cell Interactions
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC112437/
https://ncbi.nlm.nih.gov/pubmed/11090154
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