Expression of an Altered Ribonucleotide Reductase Activity Associated with the Replication of Murine Cytomegalovirus in Quiescent Fibroblasts

Ribonucleotide reductase (RNR) is an essential enzyme for the de novo synthesis of both cellular and viral DNA and catalyzes the conversion of ribonucleoside diphosphates into the corresponding deoxyribonucleoside diphosphates. The enzyme consists of two nonidentical subunits, termed R1 and R2, whos...

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Main Authors: Lembo, David, Gribaudo, Giorgio, Hofer, Anders, Riera, Ludovica, Cornaglia, Maura, Mondo, Alessandra, Angeretti, Alessandra, Gariglio, Marisa, Thelander, Lars, Landolfo, Santo
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2000
Assuntos:
Virus-Cell Interactions
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC112436/
https://ncbi.nlm.nih.gov/pubmed/11090153
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