Expression of an Altered Ribonucleotide Reductase Activity Associated with the Replication of Murine Cytomegalovirus in Quiescent Fibroblasts

Ribonucleotide reductase (RNR) is an essential enzyme for the de novo synthesis of both cellular and viral DNA and catalyzes the conversion of ribonucleoside diphosphates into the corresponding deoxyribonucleoside diphosphates. The enzyme consists of two nonidentical subunits, termed R1 and R2, whos...

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Detalhes bibliográficos
Main Authors: Lembo, David, Gribaudo, Giorgio, Hofer, Anders, Riera, Ludovica, Cornaglia, Maura, Mondo, Alessandra, Angeretti, Alessandra, Gariglio, Marisa, Thelander, Lars, Landolfo, Santo
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2000
Assuntos:
Virus-Cell Interactions
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC112436/
https://ncbi.nlm.nih.gov/pubmed/11090153
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