High-Titer, Wild-Type Free Recombinant Adeno-Associated Virus Vector Production Using Intron-Containing Helper Plasmids

Recombinant adeno-associated virus (rAAV) is capable of directing long-term, high-level transgene expression without destructive cell-mediated immune responses. However, traditional packaging methods for rAAV vectors are generally inefficient and contaminated with replication-competent AAV (rcAAV) p...

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Detalles Bibliográficos

Publicado en:	J Virol
Autores principales:	Cao, Lei, Liu, Yuhong, During, Matthew J., Xiao, Weidong
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	American Society for Microbiology (ASM) 2000
Materias:	Gene Therapy
Acceso en línea:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC112424/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11090141/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.74.24.11456-11463.2000
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