Structure-Based Moloney Murine Leukemia Virus Reverse Transcriptase Mutants with Altered Intracellular Direct-Repeat Deletion Frequencies

Template switching rates of Moloney murine leukemia virus reverse transcriptase mutants were tested using a retroviral vector-based direct-repeat deletion assay. The reverse transcriptase mutants contained alterations in residues that modeling of substrates into the catalytic core had suggested migh...

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Autors principals: Pfeiffer, Julie K., Georgiadis, Millie M., Telesnitsky, Alice
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2000
Matèries:
Replication
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC112395/
https://ncbi.nlm.nih.gov/pubmed/11000235
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