Structure-Based Moloney Murine Leukemia Virus Reverse Transcriptase Mutants with Altered Intracellular Direct-Repeat Deletion Frequencies

Template switching rates of Moloney murine leukemia virus reverse transcriptase mutants were tested using a retroviral vector-based direct-repeat deletion assay. The reverse transcriptase mutants contained alterations in residues that modeling of substrates into the catalytic core had suggested migh...

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Main Authors: Pfeiffer, Julie K., Georgiadis, Millie M., Telesnitsky, Alice
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Society for Microbiology 2000
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Replication
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC112395/
https://ncbi.nlm.nih.gov/pubmed/11000235
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