Unusual Distribution of Mutations Associated with Serial Bottleneck Passages of Human Immunodeficiency Virus Type 1
Repeated bottleneck passages result in fitness losses of RNA viruses. In the case of human immunodeficiency virus type 1 (HIV-1), decreases in fitness after a limited number of plaque-to-plaque transfers in MT-4 cells were very drastic. Here we report an analysis of entire genomic nucleotide sequenc...
Sparad:
| I publikationen: | J Virol |
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| Huvudupphov: | , , |
| Materialtyp: | Artigo |
| Språk: | Inglês |
| Utgiven: |
American Society for Microbiology (ASM)
2000
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| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC112385/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11000225/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.74.20.9546-9552.2000 |
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