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Adeno-Associated Virus Type 2 Rep78 Induces Apoptosis through Caspase Activation Independently of p53

Adeno-associated virus (AAV) type 2 Rep78 is a multifunctional protein required for AAV DNA replication, integration, and gene regulation. The biochemical activities of Rep78 have been described, but the effects of Rep proteins on the cell have not been characterized. We have analyzed Rep-mediated c...

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Библиографические подробности
Опубликовано в::J Virol
Главные авторы: Schmidt, Michael, Afione, Sandra, Kotin, Robert M.
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Microbiology (ASM) 2000
Предметы:
Online-ссылка:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC112373/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11000213/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.74.20.9441-9450.2000
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