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Adeno-Associated Virus Type 2 Rep78 Induces Apoptosis through Caspase Activation Independently of p53

Adeno-associated virus (AAV) type 2 Rep78 is a multifunctional protein required for AAV DNA replication, integration, and gene regulation. The biochemical activities of Rep78 have been described, but the effects of Rep proteins on the cell have not been characterized. We have analyzed Rep-mediated c...

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Hlavní autoři: Schmidt, Michael, Afione, Sandra, Kotin, Robert M.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2000
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC112373/
https://ncbi.nlm.nih.gov/pubmed/11000213
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