E2F Proteins Are Posttranslationally Modified Concomitantly with a Reduction in Nuclear Binding Activity in Cells Infected with Herpes Simplex Virus 1

The transition from G(1) to S phase in the cell cycle requires sequential activation of cyclin-dependent kinase 4 (cdk4) and cdk2, which phosphorylate the retinoblastoma protein, causing the release of E2F. Free E2F upregulates the transcription of genes involved in S phase and cell cycle progressio...

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Библиографические подробности

Опубликовано в::	J Virol
Главные авторы:	Advani, Sunil J., Weichselbaum, Ralph R., Roizman, Bernard
Формат:	Artigo
Язык:	Inglês
Опубликовано:	American Society for Microbiology (ASM) 2000
Предметы:	Virus-Cell Interactions
Online-ссылка:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC112314/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10933691/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.74.17.7842-7850.2000
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