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Apical Gene Transfer into Quiescent Human and Canine Polarized Intestinal Epithelial Cells by Lentivirus Vectors

Intestinal epithelial cells secrete a protective luminal mucus barrier inhibiting viral gene transfer. Quiescent, polarized monolayers of primary epithelial cells from dog gallbladder and human colon are efficiently transduced through the apical mucus side by lentivirus vectors, suggesting their app...

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Detalhes bibliográficos
Main Authors: Seppen, Jurgen, Barry, Simon C., Klinkspoor, J. Henriette, Katen, Louis J., Lee, Sum P., Garcia, J. Victor, Osborne, William R. A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2000
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC112286/
https://ncbi.nlm.nih.gov/pubmed/10906219
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