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The Karyophilic Properties of Human Immunodeficiency Virus Type 1 Integrase Are Not Required for Nuclear Import of Proviral DNA

Integrase (IN) is a key component of the preintegration nucleoprotein complex (PIC), which transports the retroviral genome from the cytoplasm to the nucleus of newly infected cells. Retroviral IN proteins have intrinsic karyophilic properties, which for human immunodeficiency virus type 1 (HIV-1) a...

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Publicado en:J Virol
Autores principales: Petit, Caroline, Schwartz, Olivier, Mammano, Fabrizio
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology (ASM) 2000
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Acceso en línea:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC112230/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10888652/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.74.15.7119-7126.2000
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