Effects of Palmitoylation of Replicase Protein nsP1 on Alphavirus Infection

The membrane-associated alphavirus RNA replication complex contains four virus-encoded subunits, the nonstructural proteins nsP1 to nsP4. Semliki Forest virus (SFV) nsP1 is hydrophobically modified by palmitoylation of cysteines 418 to 420. Here we show that Sindbis virus nsP1 is also palmitoylated...

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Bibliografiske detaljer
Main Authors: Ahola, Tero, Kujala, Pekka, Tuittila, Minna, Blom, Titta, Laakkonen, Pirjo, Hinkkanen, Ari, Auvinen, Petri
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2000
Fag:
Replication
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC112188/
https://ncbi.nlm.nih.gov/pubmed/10888610
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