Inhibition of Human Immunodeficiency Virus Type 1 Replication in Primary CD4(+) T Lymphocytes, Monocytes, and Dendritic Cells by Cytotoxic T Lymphocytes

We demonstrate that human immunodeficiency virus type 1 (HIV-1)-specific CD8(+) cytotoxic T lymphocytes (CTL) suppress HIV-1 replication in primary lymphocytes, monocytes, and dendritic cells individually. Viral inhibition is significantly diminished in lymphocyte-dendritic cell clusters, suggesting...

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Detalhes bibliográficos

Publicado no:	J Virol
Principais autores:	Severino, Michael E., Sipsas, Nikolaos V., Nguyen, Phuong Thi, Kalams, Spyros A., Walker, Bruce D., Johnson, R. Paul, Yang, Otto O.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 2000
Assuntos:	Pathogenesis and Immunity
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC112184/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10864688/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.74.14.6695-6699.2000
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