Replacement of the Ectodomains of the Hemagglutinin-Neuraminidase and Fusion Glycoproteins of Recombinant Parainfluenza Virus Type 3 (PIV3) with Their Counterparts from PIV2 Yields Attenuated PIV2 Vaccine Candidates

We sought to develop a live attenuated parainfluenza virus type 2 (PIV2) vaccine strain for use in infants and young children, using reverse genetic techniques that previously were used to rapidly produce a live attenuated PIV1 vaccine candidate. The PIV1 vaccine candidate, designated rPIV3-1cp45, w...

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Bibliografische Detailangaben

Veröffentlicht in:	J Virol
Hauptverfasser:	Tao, Tao, Skiadopoulos, Mario H., Davoodi, Fatemeh, Riggs, Jeffrey M., Collins, Peter L., Murphy, Brian R.
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Microbiology (ASM) 2000
Schlagworte:	Vaccines and Antiviral Agents
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC112153/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10864657/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.74.14.6448-6458.2000
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