Differences between C57BL/6 and BALB/cBy Mice in Mortality and Virus Replication after Intranasal Infection with Neuroadapted Sindbis Virus

Neuroadapted Sindbis virus (NSV), given intranasally, caused fatal encephalitis in 100% of adult C57BL/6 mice and 0% of BALB/cBy mice. Most C57BL/6 mice developed severe kyphoscoliosis followed by hind-limb paralysis, while BALB/cBy mice did not. In situ hybridization for detecting NSV RNA and immun...

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הוצא לאור ב:	J Virol
Principais autores:	Thach, Dzung C., Kimura, Takashi, Griffin, Diane E.
פורמט:	Artigo
שפה:	Inglês
יצא לאור:	American Society for Microbiology (ASM) 2000
נושאים:	Pathogenesis and Immunity
גישה מקוונת:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC112114/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10846099/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.74.13.6156-6161.2000
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