Tumor-Specific, Replication-Competent Adenovirus Vectors Overexpressing the Adenovirus Death Protein

We have constructed two novel adenovirus (Ad) replication-competent vectors, named KD1 and KD3, that may have use in anticancer therapy. The vectors have two key features. First, they markedly overexpress the Ad death protein (ADP), an Ad nuclear membrane glycoprotein required at late stages of infe...

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Detalhes bibliográficos

Publicado no:	J Virol
Principais autores:	Doronin, Konstantin, Toth, Karoly, Kuppuswamy, Mohan, Ward, Peter, Tollefson, Ann E., Wold, William S. M.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 2000
Assuntos:	Gene Therapy
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC112113/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10846098/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.74.13.6147-6155.2000
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